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Research

Pycnogenol Improves Endothelial Function

A study published in European Heart Journal examines patients with coronary artery disease and the effects of natural supplement Pycnogenol, an antioxidant plant extract from the bark of the French maritime pine tree, and a recognized natural solution for heart health. The study found that Pycnogenol naturally improves endothelial function in patients with stable coronary artery disease. The randomized, double-blind, placebo-controlled, crossover study was carried out at the Clinic for Cardiology at the University Hospital Zurich in Switzerland. The study investigated 23 patients with stable coronary artery disease, as documented by coronary angiography. Pycnogenol and placebo tablets were prepared in identical capsules to ensure uniform appearance of both formulations. Patients in Group One received Pycnogenol (200 mg/d) for eight weeks followed by a two-week washout-period, then took placebo for another eight weeks. Group Two received the opposite sequence of placebo first, then two weeks wash-out, followed by eight weeks with Pycnogenol (200 mg/d). After eight weeks of treatment with Pycnogenol, artery dilatation increased significantly by 32 percent, while it remained unchanged in the placebo group.
For further information: www.pycnogenol.com

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